Quantitative Molecular Pharmacology and Informatics in Drug Discovery
Michael William Lutz, Terrence Kenakin · Medical Entomology and Zoology · 1999
Drug Discovery. Measurement of Drug Affinity. Efficacy. Pharmacological Assays Used in Screening for Therapeutic Ligands. Finding the Optimal Assay Format for the Chemical Target. Mathematical and Statistical Framework for Problems in Drug Discovery. Statistical Methods for Target Identification and Validation. Experimental Design. Analysis and Interpretation of Data. Index.