Integrating ontologies and argumentation for decision-making in breast cancer
M.H. Williams · 2009
I, Matthew Hardy Williams, confirm that the work presented in this thesis is my own. Where information This thesis describes some of the problems in providing care for patients with breast cancer. These are then used to motivate the development of an extension to an existing theory of argumentation, which I call the Ontology-based Argumentation Formalism (OAF). The work is assessed in both theoretical and empirical ways. From a clinical perspective, there is a problem with the provision of care. Numerous reports have noted the failure to provide uniformly high quality care, as well as the number of deaths caused by medical care. The medical profession has responded in various ways, but one of these has been the development of Decision Support Systems (DSS). The evidence for the effectiveness of such systems is mixed, and the technical basis of such systems remains open to debate. However, one basis that has been used is argumentation. An important aspect of clinical practice is the use of the evidence from clinical trials, but these trials are based on the results in defined groups of patients. Thus when we use the results of clinical trials to reason about treatments, there are two forms of information we are interested in- the evidence from