Molecular Diversity in Drug Design
Philip M. Dean, Richard A. Lewis · Kluwer Academic Publishers eBooks · 2002
Contributors. Acknowledgements. Preface. Issues in Molecular Diversity and the Role of Ligand Binding Sites J. Smith, et al. Molecular Diversity in Drug Design. Application to High-Speed Synthesis and High-Throughput Screening C.G. Newton. Background Theory of Molecular Diversity V.J. Gillet. Absolute vs Relative Similarity and Diversity J.S. Mason. Diversity in Very Large Libraries L. Weber, M. Almstetter. Subset-Selection Methods For Chemical Databases P. Willett. Molecular Diversity in Site-focused Libraries D.C. Roe. Managing Combinatorial Chemistry Information K. Davies, C. White. Design of Small Libraries for Lead Exploration P.M. Andersson, et al. The Design of Small- and Medium-sized Focused Combinatorial Libraries R.C. Lewis. Index.