A Mathematical Model for a New Kind of Drug Administration by using R.B.C.(Mathematical Topics in Biology)
Edoardo Beretta, F. Solimano, Y. Takéuchi · Institutional Repositories DataBase (IRDB) · 1994
A mathematical model for the drug delivery to tissues by using a preassigned cohort of red blood cells (RBC) loaded with a drug is presented.The model has a discrete time delay in the interaction between RBC and macrophage cells in the various tissues.A control problem to maintain the longest duration of the therapeutic effect is considered.