Protein-Ligand Interactions
Methods and principles in medicinal chemistry · 2003
Preface.A Personal Foreword.List of Contributors.List of Abbreviations.Prologue (D. Brown).Prediction of Non-bonded Interactions in Drug Design (H. Bohm).Introduction to Molecular Recognition Models (H. Schneider).Experimental Approaches to Determine the Thermodynamics of Protein-Ligand Interactions (R. Raffa).The Biophore Concept (S. Pickett).Receptor-Ligand Interaction (M. Hofliger & A. Beck-Sickinger).Hydrogen Bonds in Protein-Ligand Complexes (M. Williams & J. Ladbury).Principles of Enzyme-Inhibitor Design (D. Banner).Tailoring Protein Scaffolds for Ligand Recognition (A. Skerra).Small Molecule Screening on Chemical Microarrays (G. Metz, et al.).Subject Index.