Computational Drug Design For Rare And Neglected Diseases: A Systematic Review of Unused Opportunities
P Ashwini, Puttagunta Varshini, Satish. P, Patlolla Ruchitha, Sowmya. P, Sridhar. S · International Journal of Research in Pharmacology & Pharmacotherapeutics · 2025
Computer-Aided Drug Design (CADD), which bridges the fields of biology and technology, is a revolutionary force in the ever-changing field of drug development. The historical development of CADD, its classification into structure-based and ligand-based techniques, and its critical function in streamlining and accelerating drug discovery are all covered in this study. The process of designing and developing new drugs is expensive and time-consuming. These days, computer-aided drug design techniques are typically employed to increase the effectiveness of medication discovery and advancement. Computer-Aided Drug Design (CADD) is a broad field that incorporates both basic and applied analysis in many forms. It is being used in a number of disciplines, such as nanotechnology, molecular biology, and biochemistry. The pharmaceutical business and research frequently use computational tools to increase the efficacy of medication discovery and development.