The Human Organ Atlas

Claire Walsh, Joseph Brunet, David Stansby, Guillaume Gaisné, Yang Zhou, Maximilian Ackermann, Alexandre Bellier, Camille Berruyer, Axel Bocciarelli, Marjolaine Bodin, Bernadette S. de Bakker, Hector Dejea, Alejandro De Maria Antolinos, Klaus Engel, Andrew Götz, Joseph Jacob, Danny David Jonigk, Joanna Purzycka, Theresa A. Urban, Stijn E. Verleden · bioRxiv (Cold Spring Harbor Laboratory) · 2025

We present the Human Organ Atlas (HOA), an open data repository making accessible multiscale 3D imaging of human organs. The repository also provides software tools and training resources enabling worldwide access, sharing, and analysis of these datasets, facilitating further research and the continued expansion of the HOA. The images are generated using a synchrotron imaging technique - Hierarchical Phase-Contrast Tomography (HiP-CT) that uses the ESRF's Extremely Brilliant Source, spanning whole organ imaging at around 20 μm/voxel with local volumes of interest within the intact organs imaged down to ~ 1 μm/voxel. This offers a comprehensive exploration of human anatomy, providing unparalleled insights into intricate structures and spatial relationships. The Human Organ Atlas offers researchers, clinicians, and educators a valuable resource for anatomical study, image analysis, medical education, and large-scale data mining.

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