Cancer Detection in Breast MRI Screening via Explainable AI Anomaly Detection

Felipe Oviedo, Anum S. Kazerouni, Philipp Liznerski, Yixi Xu, Michael Hirano, Robert A. Vandermeulen, Marius Kloft, Elyse Blum, Adam Michael Alessio, Christopher I. Li, William Brinson Weeks, Rahul M. Dodhia, Juan Lavista Ferres, Habib Rahbar, Savannah C. Partridge · Radiology · 2025

An anomaly detection model for breast cancer on MRI scans achieved high performance, surpassing binary classification in high- and low-cancer-prevalence scenarios and producing explanation heat maps not significantly different from radiologist annotations.

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