Theoretical Model of Thiophene and Its Derivatives Interaction with BRCA-1
Lauro Figueroa-Valverde, Rosas‐Nexticapa Marcela, Magdalena Alvarez-Ramirez, López‐Ramos Maria, Virginia Mateu-Armand, Hernandez-Vazquez Patricia · Asian journal of Current Research in Clinical Cancer · 2024
Research indicates a growing association between breast cancer and increased mortality rates across the globe. Various risk factors, such as obesity, high-fat diets, lack of physical exercise, alcohol use, oral contraceptive consumption, genetic mutations, and others, contribute to the development of breast cancer. In addition, some studies have pointed to the role of the breast cancer gene 1 (BRCA1) in breast cancer onset. The objective of this study was to investigate how thiophene (1) and its