A REVIEW ON MANAGEMENT OF COPD WITH SPCIFIED STUDY ON PRE-CLINICAL SCREENING METHODS FOR PHARMACOLOGICAL ACTIVITY
International Journal of Biology Pharmacy and Allied Sciences · 2025
Chronic Obstructive Pulmonary Disease (COPD) is characterized to be heterogenous lung disease, where patient experiences chronic cough, sputum production and exacerbation.Many people were diseased globally due to exposure of toxic substances, lack of respiratory hygiene and genetic abnormalities.As per Global Burden of Diseases COPD is "third leading cause of death worldwide".In concern of these challenges, Global Initiative for Chronic Obstructive Lung Disease have programmed policies and strategies in prevention and management of COPD.In this article we discuss about efficient diagnostic like Spirometry, CT, CBC, Lung Function test and treatment procedures like Medication, Oxygen therapy, Rehabitation, Vaccination and Surgical procedures.This article mainly highlights in detail on Pre-clinical screening methods like In-vitro and In-vivo model for Pharmacological activity.