Machine Learning to Improve Decision Support for Preventing Adverse Drug Events

Tora Hammar, Daniel Nilsson, Olof Björneld, Celina Sving, Alisa Lincke · Studies in health technology and informatics · 2025

One approach to preventing adverse drug events (ADEs), such as harmful drug interactions, is the implementation of clinical decision support systems (CDSS). In an ongoing project, we are investigating the accuracy of the rule-based CDSS currently utilized in Swedish healthcare for predicting ADEs and exploring whether machine learning (ML) can improve these predictions. By analyzing real-world healthcare data from a Swedish region spanning a 10-year period, we show that ML has potential to improve ADE predictions compared to existing rule-based CDSS.

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