High input impedance and power efficient instrumentation amplifier for biomedical applications
Pravej Kumar Tanwar, Sandeep Singh Gill, Balwinder Raj · IET conference proceedings. · 2025
The design and optimization of different topologies based amplifier presented in this paper and these instrumentations amplifier specifically tailored for biomedical applications. The proposed amplifiers aim to provide high common-mode rejection, low noise, and optimal performance for the amplification of weak biomedical signals. The design methodology involves the integration of a differential amplifier at the core of the instrumentation amplifier architecture. Operational amplifiers with low input noise and high precision are selected to ensure the amplifier’s sensitivity to minute physiological signals. The resistor values and feedback networks are carefully chosen through simulation and optimization to obtain the targeted gain, bandwidth, and common-mode rejection characteristics. Performance metrics, including CMRR, noise levels, and bandwidth, are rigorously analyzed. The differential amplifier configuration enhances the CMRR, surpassing 100 dB, thus effectively eliminating common-mode interference in biomedical signal acquisition. The amplifiers achieves low noise levels crucial for maintaining signal fidelity, and a wide bandwidth accommodates diverse biomedical signals encountered in applications such as a physiological measurements.