Monkeypox Disease Classification from Skin Lesion Images using Deep Convolution Neural Network

Rajasekaran Thangaraj, Balasubramaniam Vadivel, S. Manoj Kumar, S. Sadesh, Priya Karunakaran, P. Prakash · 2025

Recently monkeypox outbreak has raised concerns due to its increasing number of cases and diverse dermatological symptoms in 2024, which can complicate early diagnosis due to similarities with other viral infections such as measles and chickenpox. To enhance diagnostic accuracy, transfer learning models and artificial intelligence (AI) have been explored as effective tools. Pre-trained models such as VGG16, VGG19, ResNet50V2, and MobileNetV2 have been employed for monkeypox detection, each with distinct trade-offs in terms of computational efficiency and diagnostic precision. MobileNetV2 offers superior efficiency, but this comes at the cost of reduced accuracy. VGG models provide higher accuracy but require much more computational power.Among these models, DenseNet121 stands out by achieving 99% accuracy while requiring 37% less computational power, making it the model optimized choice for efficient and accurate monkeypox classification.

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