Periodic Graphics: The science of weight-loss drugs

special to C EN Andy Brunning · C&EN Global Enterprise · 2025

Chemical educator and Compound Interest blogger Andy Brunning explores the blockbuster weight-loss drugs called GLP-1 receptor agonists To download a pdf of this article, visit http://cenm.ag/weightlossdrugs. References used to create this graphic: Alfaris, Nasreen, Stephanie Waldrop, Veronica Johnson, Brunna Boaventura, Karla Kendrick, and Fatima Cody Stanford. “GLP-1 Single, Dual, and Triple Receptor Agonists for Treating Type 2 Diabetes and Obesity: A Narrative Review.” eClinicalMedicine (September 2024). DOI: 10.1016/j.eclinm.2024.102782. Ghusn, Wissam, Alan De la Rosa, Daniel Sacoto, Lizeth Cifuentes, Alejandro Campos, Fauzi Feris, Maria Daniela Hurtado, and Andres Acosta. “Weight Loss Outcomes Associated with Semaglutide Treatment for Patients with Overweight or Obesity.” JAMA Network Open (Sept. 2022). DOI: 10.1001/jamanetworkopen.2022.31982. Liu, Yupeng, Binye Ruan, Huinan Jiang, Siyu Le, Yi Liu, Xuemei Ao, Yufeng Huang, et al. “The Weight-Loss Effect of GLP-1RAs Glucagon-Like Peptide-1 Receptor Agonists in Non-diabetic Individuals with Overweight or Obesity: A Systematic Review with Meta-analysis and Trial Sequential Analysis of

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