Multi-Modal CNN-Ensemble Learning with Pansegnet for Early and Accurate Pancreatic Cancer Analysis
A. Kavitha, Dhanush Sriram R, Arunkumar Rajendran · 2024
Pancreatic cancer is one of the deadliest types of cancer, as it is mostly diagnosed at an advanced stage because no such method to detect this in its preliminary stages exists. This research work now tries to introduce a new method for early and accurate pancreatic cancer analysis by introducing a multimodal CNN-ensemble combined with the latest segmentation techniques, Pansegnet. The proposed system combines histopathological imaging with genomic data to capture both the morphological and genetic variations in pancreatic cancer. This model makes use of the ensemble of CNN architecture through the exploitation of the strong multi-network that improves the accuracy of its prediction. The pansegnet, being a very efficient segmentation model, brings about accurate localization of the tumors which can further be taken into fine-tuning feature extraction toward classification and prediction tasks. Survival is analyzed post-surgery using clinical data through Cox Proportional Hazards and a deep learning-based survival model to predict the outcome of a patient. A multi-modal ensemble-learning framework demonstrates superior performance in the early detection and survival prediction of patients and can be applied to personalized treatment strategies and improved prognosis of patients. The bottom line is that imaging and genomic data need to be combined for a holistic analysis. In developing an integrated model that combines CNN-based feature extraction for high-resolution image analysis, FNN/RNN for processing structured genomic and clinical data, and ensemble learning to enhance reliability in both tumor classification and survival prediction. Additionally, introduced self-adaptive feature fusion mechanism, allowing for detailed multi-scale feature representation and contextual understanding essential for capturing complex tumor morphology and individual genomic variations.