Network‐based Methods in Drug Discovery
Ghanshyam Ratilal Parmar, Ashish S. Shah, Jay Mukesh Chudasama, Priya Kashav, Vanesa James · 2024
“Network-Based Methods in Drug Discovery” explores the use of network science principles and computational tools in drug discovery. Researchers use network analysis to understand the intricate connections between biological elements like proteins, genes, and metabolites, revealing causes of disease and potential therapeutic targets. Techniques like protein–protein interaction networks, gene regulatory networks, and metabolic networks help identify molecular interactions and processes involved in disease development. This chapter discusses the use of computer techniques and tools to analyze and interpret intricate biological networks, enabling the identification of potential drugs for further experimental validation. This chapter also emphasizes the significant impact of network science on expediting drug discovery, promoting innovation, and advancing precision medicine efforts.