Text-guided small molecule generation via diffusion model
Yanchen Luo, Junfeng Fang, Sihang Li, Zhiyuan Liu, Jiancan Wu, An Zhang, Wenjie Du, Xiang Wang · iScience · 2024
, which integrates language and diffusion models for text-guided small molecule generation. This method uses textual conditions to guide molecule generation, enhancing both stability and diversity. Experimental results show TextSMOG's proficiency in capturing and utilizing information from textual descriptions, making it a powerful tool for generating 3D molecular structures in response to complex textual customizations.