Computational biology approach to predict molecular mechanism in cancer
Ansari Vikhar Danish Ahmad, Subur W. Khan, Qazi Yasar, Mohd Sayeed Shaikh, Mohd Mukhtar Khan · Oral Oncology Reports · 2024
The field of biology offers a complete structure for studying intricate molecular interactions and the strength of bonding between molecules but with an emphasis on developing treatments and discovering markers in medicine research that hold promise for targeting specific diseases like cancer subtypes effectively by pinpointing crucial signals and pathways crucial for tumor development growth, alongside network analysis as a potent tool to foresee how small molecules interact with proteins linked to cancer and determine promising new treatments. This methodical strategy enables the evaluation of potential medications by assessing their capacity to bind effectively to cancer causing targets for enhanced treatment accuracy." Additionally integrating machine learning methods with multi dataset analyses greatly enhances the thorough examination of cancer associated molecular connections ultimately streamlining drug development and biomarker discovery. This underscores the importance of molecular docking in forecasting interactions, between drugs and their targets within the realm of cancer bioinformatics. • Employ computational models in the simulation and analysis of signal transduction pathways in cancers. • Drug targets prediction based on network pharmacology and molecular docking in an integrated approach. • Gene Expression involves the use of bioinformatic tools to correlate gene expression patterns with tumor progression. • Structural Insights Apply structural bioinformatics to predict what mutations disrupt protein function in cancer.