A 28nm Approximate / Binary 6T CAM for Sequence Alignment
Brian Crafton, Samuel D. Spetalnick, Muya Chang, Arijit Raychowdhury · 2024
A dense 6T CAM implementing exact and approximate search for sequence alignment is presented. Conventional binary CAM (BCAM) returns a match when the search and stored strings match exactly, approximate CAM (A CAM) returns a match when the hamming distance (HD) between the search and stored strings is within some tolerance. Using a 6T 28nm SRAM bitcell, high density (2.54 Mb/mm2) is achieved, the macro operates up to 200MHz and consumes 0.77fJ/search/bit (BCAM) and 2.37fJ/search/bit (ACAM).