Network pharmacology and single-cell transcriptomic analysis with molecular docking to elucidate the potential compounds and targets of Polygonum cuspidatum Sieb.et Zucc. for hepatocellular carcinoma
Wenze Wu, Yuzhu Shi, Yongzi Wu, Rui Zhang, Xinyan Wu, Weidi Zhao, Zhiyuan Chen, Gang Ye · iLiver · 2024
Background and aims: for these effects have not yet been revealed. Methods: for hepatocellular carcinoma. Results: , physcion diglucoside was found to have the most potential to treat hepatocellular carcinoma by targeting CDK1. Conclusion: , which could serve as a scientific basis for its development as a medicinal resource and the targeting of CDK1 for hepatocellular carcinoma treatment.