Modalities Guided Latent Diffusion Model for Brain MRI Synthesis

Xiaoliang Lei, Xiaosheng Yu, Maocheng Bai, Chengdong Wu · 2024

Brain MRI synthesis technology addresses the challenge of missing MRI modalities in the clinical domain. We strongly emphasize harnessing the full potential of multi-modal MRI data and the spatial correlations within brain structures, so we proposed a method for synthesizing brain MRI images. This method distills latent information from available MRI modalities, providing guidance for synthesizing the missing MRI modality, thereby transcending the constraints of spatial structural relevance within the task of 3D brain MRI image synthesizing. Our experiments demonstrate that our method can generate high-quality 3D brain MRI images.

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