A MONUMENTAL CRUSADE OF METHYLENE BLUE FROM A STAINING DYE TOWARDS A POTENTIAL DRUG CANDIDATE FOR INNUMERABLE DISEASES: A COMPREHENSIVE REVIEW
International Journal of Biology Pharmacy and Allied Sciences · 2024
Methylene blue, also known as methylthionium ion, is an organic chloride salt having phenothiazine heterocyclic ring.Initially, it was synthesized as a dye.Methylene blue is an active inhibitor of enzymes like nitric oxide synthase and guanylate cyclase.For the same reason, it was used to treat cyanide poisoning and urinary tract infections in previous years.Now-a-days, methylene blue is the most promising agent to treat innumerable diseases like methemoglobinemia, psoriasis, septic shock, and ifosfamide toxicity.It is under research for the treatment of disparate diseases like malaria, bipolar disorder, AIDS related kaposi's sarcoma, west nile virus, HIV-1 virus etc.This agent has truly accomplished its journey from a staining dye to a potential drug candidate.