MANCIE: Matrix Analysis and Normalization by Concordant Information Enhancement
Tao Wang, Chongzhi Zang · 2015
High-dimensional data integration is a critical but difficult problem in genomics research because of potential biases from high-throughput experiments. We present MANCIE, a computational method for integrating two genomic data sets with homogenous dimensions from different sources based on a PCA procedure as an approximation to a Bayesian approach.