Interaction of Thiophene and Their Derivatives with BRCA-1 Using a Theoretical Model
Lauro Figueroa-Valverde, Rosas‐Nexticapa Marcela, Magdalena Alvarez-Ramirez, López‐Ramos Maria, Virginia Mateu-Armand, Hernandez-Vazquez Patricia · Clinical Cancer Investigation Journal · 2024
Several studies indicate that breast cancer has been associated with increases in mortality rates worldwide. There are several risk factors to developed breast cancer such as obesity, high fat diet, Lack of physical activity, alcohol, use of oral contraceptives, genetic mutations, and others. In addition, some reports suggesting that breast cancer gene 1 (BRCA1) has been related to breast cancer development. This research aimed to determine the possible interaction of thiophene (1) and their ana