Advances in decision support for diagnosis and early management of acute leukaemia
Amin Taha Turki, Merlin Engelke, Marta Sobas · The Lancet Digital Health · 2024
Acute leukaemia includes several life-threatening malignancies, mainly acute myeloid leukaemia (AML) and acute lymphocytic leukaemia (ALL). Although long-term patient outcomes depend on disease-related genomic factors that translate into treatment resistance and relapse, early mortality remains a substantial concern, especially in people with acute promyelocytic leukaemia (APL). Despite genomic or flow-cytometry diagnostics, traditional morphological examination remains the primary method of diagnosis.