Evolution of the Drug Repurposing Paradigm
Igor Yu Malyshev, Shabunina EA, Kuznetsova LV, Lobanov EV · Journal of Pathology Research Reviews & Reports · 2024
The appearance of novel diseases like COVID-19, as well as the resistance of severe diseases to existing medications, have caused a need for new drugs to be developed quickly. The concept of drug repurposing has been offered to increase efficiency and minimise time and financial costs associated with drug development. Repurposing is a strategy for discovering new medical applications for already approved drugs. The study covers recent computational and experimental approaches for finding drug candidates for repurposing, as well as the challenges that arise along the way.