Improving Breast Cancer Detection with Convolutional Neural Networks and Modified ResNet Architecture

Javad Nouri Pour, Mohammad Ali Pourmina, Mohammad Naser Moghaddasi · Current Medical Imaging Formerly Current Medical Imaging Reviews · 2024

BACKGROUND: The pathogenesis of breast cancer is characterized by dysregulated cell proliferation, leading to the formation of a neoplastic mass. Conventional methodologies for analyzing carcinomatous distal areas within whole-slide images (WSIs) tissue regions may lack comprehensive insights. PURPOSE: This study aims to introduce an innovative methodology based on convolutional neural networks (CNN), specifically employing a CNN Modified ResNet architecture for breast cancer detection. The research seeks to address the limitations of existing approaches and provide a robust solution for the comprehensive analysis of tissue regions. METHODS: The dataset utilized in this study comprises approximately 275,000 RGB image patches, each standardized at 50x50 pixels. The CNN Modified ResNet architecture is implemented, and a comparative evaluation against diverse architectures is conducted. Rigorous validation tests employing established performance metrics are carried out to assess the proposed methodology. RESULTS: The proposed architecture achieves a notable 89% accuracy in breast cancer detection, surpassing alternative methods by 2%. The results signify the efficacy and superiority of the CNN Modified ResNet model in analyzing carcinomatous distal areas within WSIs tissue regions. CONCLUSION: In conclusion, this study demonstrates the potential of the CNN Modified ResNet architecture as an effective tool for breast cancer detection. The enhanced accuracy and comprehensive analysis capabilities make it a promising approach for advancing the understanding of neoplastic masses in WSIs tissue regions. Further research and validation could solidify its role in clinical applications and diagnostic procedures.

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