Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 7
Yuri M. Efremov · Figshare · 2022
A comparison of therapies with anti-PCSK9 antibodies and small-molecule inhibitors. Due to higher association rate and lower dissociation rate, application of the inhibitory molecules (red curve, set 1) at the same concentration as antibodies (blue curve, set 2) leads to a faster and stronger decrease in the LDL level.