SARS-CoV-2 Drug Disease Gene Association
Weston, Mark, Mohammed Eslami, William Jordan · Figshare · 2020
Inspired by the White House Office of Science and Technology Policy machine-readable Coronavirus literature collection, we noticed a lack of high quality, machine-readable datasets that contained information on drug, gene, and disease associations for SARS-CoV-2. We decided to build and release an open-source dataset for the community to explore two key questions: What existing drugs have interaction potential with SARS-CoV-2? What diseases and symptoms overlap with target genes that have interaction potential with SARS-CoV-2? To address this, we compiled an integrated dataset from the following publications and resources: - A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing- The Drug Repurposing Hub: a next-generation drug library and information -resource - The DisGeNET knowledge platform for disease genomics: 2019 update