Kinalite A User-Friendly Online Tool for AutomatedVariable Time Normalization Analysis (VTNA)
Finn Bork, Sean Clark, Peter Burland, David A. Sale, Jason E. Hein · ChemRxiv · 2024
We introduce Kinalite, an innovative automation software designed to streamline kinetic analysis in chemical research. This tool utilizes concentration versus time profiles to conduct Variable Time Normalization Analysis (VTNA), effectively bypassing the trial-and-error approach and minimizing biases common in manual VTNA applications. Kinalite delivers a graphical representation of optimally aligned reaction curves, and the precise calculation of reaction orders for specified reagents. Uniquely, it provides an option to quantify the accuracy of VTNA results. Kinalite's user-friendly interface is accessible as an interactive website at https://kinalite.heinlab.com and as a GitLab repository, supporting real-time analytical capabilities. It is tailored to serve a wide spectrum of researchers, offering enhanced efficiency and accuracy in kinetic studies. Kinalite represents a significant advancement in the field, enabling deeper insights and optimizations in various chemical processes.