A brief profile of Metformin: Mechanism, Pharmacokinetics and metabolism review
Ajay Raikwar, Prashant Kumar Vinode · Advance Pharmaceutical Journal · 2023
Metformin is the most commonly prescribed drug for type 2 diabetes mellitus.In recent years, in addition to glucose lowering, several studies have presented evidence suggesting some potential role for metformin, such as antitumor effect, antiaging effect, cardiovascular protective effect, neuroprotective effect or an optional treatment for polycystic ovary syndrome.This review contains the information details with mechanism of action, various doses, their pharmacokinetics, absorption and distribution.This article also consists of detail about side effect and interaction, metabolism and elimination and various formulations available in the market.