Basic Principles of Drug Design III Designing drug molecules to fit receptors
Thomas Nogrady Donald F Weaver · 2005
Abstract The aim of this book is to provide a conceptual framework for medicinal chemistry. Chapter 1 dealt with the properties necessary to transform a molecule into a drug-like molecule. Chapter 2 described the properties that determine whether a macromolecule could be a receptor. It is now necessary to develop a method of designing drug molecules to fit into receptor molecules. The multiphore method of drug design is such a method.