Hyperspectral images classification for white blood cells with attention-aided convolutional neural networks and fusion network

Weidong Shao, Chunxu Zhang, Jinghan Wang, Xiaolin He, Dongxia Wang, Yan Lv, Yue An, Huihui Wang · Journal of Modern Optics · 2023

The classification of White blood cells (WBCs) plays an important role. However, the traditional method of blood smear analysis is laborious. This paper presented a classification method of WBCs based on hyperspectral images and Deep learning (DL). The U-net network was proposed to extract spectral features of WBCs region of interest (ROI) under the pseudo-color images with specific hyperspectral images (420.8, 557.2 and 667.4 nm). For spectral features and the pseudo-colour images of hyperspectral data, attention-aided one and two-dimensional convolutional neural networks were applied to establish WBCs classification models, respectively. The overall average accuracy can reach 94.20% and 92.60%, respectively. A fusion network was constructed to make full use of the spectral and image spatial features, and its classification accuracy reached 96.20%. In terms of overall average accuracy, the fusion network model was the optimal, but for individual types of WBCs, each network had its own unique advantages.

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