Retrospective Study on Clinical Profile of Severe Malaria in Children Admitted in a Tertiary Care Centre of Central India
Priya Verma, Uma Shankar Shukla, Ashish Kalraiya · Zenodo (CERN European Organization for Nuclear Research) · 2014
Severe malaria is a potentially fatal condition encountered in all age groups and if not treated timely can cause mortality. The present retrospective study was conducted over 4 years (2009-2012) to asses clinical and haemato- biochemical profile of all severe malaria cases admitted in pediatric ICU. Out of 179 cases of malaria, 102 (56.9%) children had severe malaria. Maximum number of patients were of plasmodium falciparum 59 (57.8%), Plasmodium vivax was documented in 13.7% and mixed infection in 27.4% cases. The age of the patients with severe malaria ranged from 4 months to 12 years mean age being 6 year. Sixty four (62.7%) of them were boys and rest of them were girls. Frequent manifestations encountered were severe anemia (65.6%), followed by impaired consciousness (20.5%), hemoglobinuria (19.6%), multiple convulsions (17.6%), circulatory collapse (10.7%), clinical icterus with multisystem involvement (11%), respiratory distress (6.8%), prostration (5.8%), spontaneous bleeding (5.8%), metabolic acidosis (3.9%) and renal impairment (1.9%). Mortality occurred only in children with Plasmodium falciparum infestation. Outcome was favourable in 88.2% children who were discharged after clinical improvement; where as 4.9% patients died and 6.86% critically ill patients left against medical advice