Advanced Applications of Computer Aided Drug Design in Pharmaceutical Sciences
Saurabh Punia, Ruchi Yadav, Preeti Upadhayay, Anupriya Kapoor, Ajay Kumar, Shashi Kiran Misra · Acta Scientific Pharmaceutical Sciences · 2023
The field of research known as computer-aided drug design (CADD) is expanding and has numerous facets.It includes a variety of practical and fundamental research facets.Both basic and applied research converge, enhancing each other's potential in the process.Quantum mechanics and molecular modelling research, including structure-based drug design, ligand-based drug design, database searching, and binding affinity based on knowledge of a biological target, are the theoretical underpinnings of CADD.Additionally, it offers alternatives for comprehending chemical systems in various ways, providing data that is difficult to collect through laboratory examination.The fact that CADD requires less time and money than laboratory studies is one of its main benefits.Therefore, the development of potential medications for treating a variety of diseases has become much more effective because to computer-aided drug design, or CADD.Drug discovery applications using the CADD methodology are advancing daily.Designing strong treatments with multiple targeted effects, more efficacies, and fewer side effects particularly hazardous one is the current trend in drug development.In this review we talk about the various applications of CADD in the field of pharmacy and healthcare system.