Discovery, synthesis and in silico approach of pyrrolo [3,4- c ]pyrroles as SARS-CoV-2 m pro inhibitors
Kailasam Saravana Mani, Rajamanikandan Sundarraj, B. Sathya Prabha · Journal of Biomolecular Structure and Dynamics · 2023
toxicity prediction using the Pro-Tox II revealed the non-toxic nature of the compounds. Hence the obtained results suggest that these compounds could be a possible anti-viral candidate and highlight this series of compounds for further drug design and development against SARS-CoV-2.Communicated by Ramaswamy H. Sarma.