Synthesis, Antimicrobial, Anthelmintic Activity, Enzymatic Degradation and Molecular Docking Studies of Some Azo Compounds containing Carvacrol Moiety
Shivaji Koshti · Asian Journal of Chemistry · 2022
In present work, the carvacrol was derivatized as azo compound by coupling method with eight different diazonium salts. The newly synthesized azo derivatives of carvacrol screened against four bacterial species and four fungal species and expressed in terms of zone of inhibition in mm and compared with standard. Furthermore, enzymatic degradation studies also been done by inoculating these newly synthesized azo derivatives with Pseudomonas aeruginosa bacterium species, which secretes the azoreductase enzyme as responsible for reduction of –N=N– linkage into two different primary aromatic amines, followed by anthelmintic activity and molecular docking study.