. Preparation and Characterization of Atorvastatin Calcium Trihydrate-cyclodextrin Inclusion Complex
Basma Mudhafar Hadi, Eman B. H. Al-Khedairy · International Journal of Drug Delivery Technology · 2022
Atorvastatin calcium (ATR) is an antihyperlipidemic agent used for lowering blood cholesterol levels. However, it is very slightly soluble in water with poor oral bioavailability, which interferes with its therapeutic action. It is classified as a class II drug according to Biopharmaceutical Classification System (low solubility and high permeability).