HRD-related morphology discovery in breast cancer by controlling for confounding factors
Yoni Schirris, Hugo M. Horlings · Cell Reports Medicine · 2022
predict homologous recombination deficiency from hematoxylin and eosin-stained slides of breast cancer tissue using deep learning. By controlling for technical artifacts on a curated dataset, the model puts forward novel HRD-related morphologies in luminal breast cancers.