Computational Predictors of the Predominant Protein Function: SARS‐CoV‐2 Case
Carlos Polanco, Manlio Fabio Márquez, Gilberto Vargas‐Alarcón · 2022
In this chapter, we describe the main molecular features of SARS-CoV-2 that cause COVID-19 disease, as well as a high-efficiency computational prediction called Polarity Index Method®. We also introduce a molecular classification of the RNA virus and DNA virus families and two main classifications: supervised and non-supervised algorithms of the predictions of the predominant function of proteins. Finally, some results obtained by the proposed non-supervised method are given, as well as some particularities found about the linear representation of proteins.