Use of Balaban F and G indices in QSAR Modeling of mutagenicity of aromatic and heteroaromic amines
Vijay K. Agrawal, Jyoti Prakash Singh, Bashcerulla Shaik · Zenodo (CERN European Organization for Nuclear Research) · 2011
Department of Applied Science, National Institute of Technical Teachers' Training & Research, Shanti Marg, Shamla Hills, Bhopal-462 002, Madhya Pradesh, India E-mail: [email protected] Department of SHM, Amrapali Institute of Technology & Sciences, Shiksha Nagar, Lamachaur. Haldwani-263 139, Uttarakhand, India E-mail : [email protected] Manuscript received 01 November 2010, accepted 02 November 2010 The recently introduced Balaban F and G indices are used for modeling mutagenicity of 95 aromatic and heteroaromic amnines acting on Salmonella typhimurium. The correlation potential of both these indices with J index is first investigated and then their combinations arc used for the mutagenic activity. The results are finally discussed using Ridge statistics.