D2.2 - Hybrid Open Datacloud and processing middleware architecture
Ignácio Blanquer, J. Damián Segrelles · Zenodo (CERN European Organization for Nuclear Research) · 2019
One of the main objectives of PRIMAGE project is to develop a hybrid open datacloud and processing middleware which comprises the use of open public and private clouds, and specific processing resources, in particular High Performance Computing (HPC) and cloud, to support predictive tools for assisting diagnosis, prognosis, therapies choice and treatment follow up, based on the use of novel imaging biomarkers, in-silico tumour growth simulation, advanced visualisation of predictions with weighted confidence scores and machine-learning based translation of this knowledge into predictors for the most relevant, disease specific, Clinical End Points. These tools (imaging biomarkers, models for in- silico medicine research, advanced visualisation tools) will be validated in the application context of two paediatric cancers, Neuroblastoma (NB, the most frequent solid cancer of early childhood) and the Diffuse Intrinsic Pontine Glioma (DIPG, the leading cause of brain tumour-related death in children). The document analyses different key scenarios of the PRIMAGE project (in the form of User Stories) from the point of view the use of data and processing resources which will determine the requirements of the middleware architecture. The domains of these scenarios are basically from the next points of views: i) application managers; ii) application developers; and iii) data managers.