Neutrosophic rule-based prediction system for toxicity effects assessment of biotransformed hepatic drugs
Sameh H. Basha, Alaa Tharwat, Areeg S. ABDALLA, Aboul Ella Hassanien · Zenodo (CERN European Organization for Nuclear Research) · 2019
Measuring toxicity is an important step in drug development. However, the current experimental meth- ods which are used to estimate the drug toxicity are expensive and need high computational efforts. Therefore, these methods are not suitable for large-scale evaluation of drug toxicity. As a consequence, there is a high demand to implement computational models that can predict drug toxicity risks. In this paper, we used a dataset that consists of 553 drugs that biotransformed in the liver.