Tuberculosis and liver fluke infection: An expressional analysis for common antioxidative pathway
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit · Biomedical and Biotechnology Research Journal (BBRJ) · 2020
Background: Tuberculosis is a common medical problem seen in several areas of the world including Indochina. The concurrence of tuberculosis with other tropical infections is possible. For those infections, the role of oxidative pathway system is widely proposed. Here, the authors study on the common antioxidative pathway of tuberculosis and liver fluke infection. Materials and Methods: This work is a bioinformatic expressional analysis. A common pathway analysis with interrelationship identification is done to on expressional antioxidative pathways of tuberculosis and liver fluke infection. Results: The common pathway can be identified with the linkage node at glutathione. Each infection contributes to increased susceptibility to each other. Conclusion: Based on the identified common antioxidative pathway, the concurrent management of both diseases at the endemic area of both liver fluke and tuberculosis infections is needed.