Approaches to Using Structure: Activity Relationship Analysis with Mechanistic Considerations to Assess Carcinogenic Hazard/Risk Potential of Chemical Substances
Anna M. Fan, George Alexeeff, Elaine Khan · 2015
Overcoming suppression and enabling immortality (e.g., immunosuppresion.p53, angiogenesis, etc.) Key mechanistic considerations Electrophile, resonance stabilization, DNA adduct, reactive oxygen species, etc.