Enzyme Catalyzed Study of Some Unsaturated Acids by N-Bromoisonicotinamide - A Kinetic Approach
International journal of advanced research in chemical sciences · 2019
Enzyme cationic micelles cetyltrimethyl ammonium bromide (CTAB) catalysed oxidation of unsaturated acids viz., acrylic and α-crotonic acid by halooxidant N-bromoisonicotinamide (NBIN) in aqueous acetic acid medium have been studied to afford corresponding products aldehydes.The reactions exhibit first-order kinetic with oxidant [NBIN] and fractional-order to concentration of unsaturated acids.The acid has shown negligible effect on rate.The study provides an evidence of complex formation between substrate and postulated species H 2 O + Br of the oxidant with stoichiometric ratio 1:2.The solvent polarity enhances the rate of oxidation whereas addition of enzyme CTAB attains almost limiting value of rate at its optimum concentration.A mechanism in consistent with the thermodynamic data and rate law have been proposed.