Kernel and regression spline smoothing techniques to estimate coefficient in rates model and its application in psoriasis
Freshteh Osmani, Ebrahim Hajizadeh, Parvin Mansouri · Medical Journal of the Islamic Republic of Iran · 2019
↑What is "already known" in this topic: Recent pharyngeal infection has been implicated in the case of psoriasis.In addition, the risk for an aggravation or an abrupt recurrence of this autoimmune disease is very high.In spite of the high incidence and recurrence rate of psoriasis in Iran, the etiological studies in this field are very sparse.→What this article adds: Data on recurrent events have been studied extensively using marginal and random effects models.In these models, it is often assumed that the effect of risk factors is unchanged over the follow-up period; however, time-dependent coefficient rates model is appropriate in situations where the effect of an exposure or covariates changes over time.