MPSM-DTI: prediction of drug–target interaction via machine learning based on the chemical structure and protein sequence
Yayuan Peng, Jiye Wang, Zengrui Wu, Lulu Zheng, Biting Wang, Guixia Liu, Weihua Li, Yun Tang · Digital Discovery · 2022
MPSM-DTI was developed for prediction of DTIs using chemical structures and protein sequences as features. Compared with other methods, MPSM-DTI reached considerable accuracy and addressed the dilemma of DTI prediction for brand new protein targets.