Is Noninferior Not Inferior?
Siri R. Kadire, Charles Corey Hardin, Katherine S. Takvorian, Chana A. Sacks · NEJM Evidence · 2022
Is Noninferior Not Inferior? What is a non-inferiority trial margin? To answer this, ask whether you have ever weighed a tradeoff between the best version of something and an acceptable alternative. Restated, in a choice between two decisions, is one option not inferior to the other? Watch an animated video that explores the basis for non-inferiority trials, the meaning of non-inferiority margins, and the interpretation of a non-inferiority trial's results.