Preclinical Drug Development Planning
Nirmala Bhogal, Robert D. Combes, Michael Balls · 2007
This chapter contains sections titled: Introduction Finding New Drug Targets Traditional Approaches to Drug Discovery and Development Special Considerations for Novel Therapeutic Classes In Vitro Assays: Applications in Safety Pharmacology Systems Biology Computational Methodology Used in Early Preclinical Drug Development Animal Models Used in Preclinical Testing of Pharmaceuticals The Use of Prior Information Conclusions Acknowledgment References